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Colchicine is a prescription drug that is primarily used to prevent gout flare-ups, and to a lesser extent, familial Mediterranean fever or FMF, in adults and children 4 years of age and older. Gout is caused by a buildup of abnormally high levels of uric acid in the blood and results in sudden pain in specific joints, most often in the big toe, ankle, or knee. FMF is an inborn condition that results in periods of pain, fever, and swelling of the stomach, lungs, and joints. Colchicine is effective at lessening the buildup of uric acid crystals and reducing swelling in the affected joints. It is important to note that Colchicine is not a general pain reliever, and will not relieve pain that is unassociated with either gout or FMF. It should not be used in such a manner.

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